Preclinical Research – Development of the model

Developing a surgical technique to relocate an implanted embryo/fetus in an animal model, for application in an ectopic pregnancy

Goal of our study: The goal of our study is to investigate the potential for developing a surgical technique that could be used to relocate an embryo/fetus in the case of an ectopic pregnancy. As it is not ethical to conduct this experimentation in humans, the goal of our work is to develop this technique in an animal (the laboratory rat) in the hope that the information can benefit humans.

While the reproductive anatomy of the rat is different from that of the human, its design gives us an opportunity to investigate a scenario that would allow us to understand the potential factors that would be involved in such a relocation. 

In summary, it is our hope that the findings from our study will provide the medical community with a foundation for the further investigation of such a surgical procedure in the human, preserving both the life of the mother and the baby.

Now Published:

Transuterine relocation of pregnant uterine horn segment in an exploratory rat model with implications for tubal ectopic pregnancy

Pregnancy-induced long-term uterine vascular remodeling in the rat

Please note: If you are unable to access the article above, please do not hesitate to email drsammutlab@gmail.com for a copy.